Who can apply
- Early-stage investigators from low- and middle-income countries
- Researchers holding an MD, PhD, MBBS or equivalent terminal research degree
- Clinical or research trainees at eligible academic or research institutions
- Faculty members or equivalent researchers at academic or research institutions
- Researchers holding established positions at organisations with adequate research infrastructure
- Eligible researchers working in non-governmental organisations
- Investigators applying as Principal Investigator for the first time on a substantial non-training research grant
Focus areas
- Paediatric HIV
- Adolescent HIV
- Prevention of vertical HIV transmission
- HIV prevention among adolescents and young people
- Cardiometabolic conditions among children and adolescents affected by HIV
- Hepatitis co-infection
- Tuberculosis co-infection
- Paediatric and adolescent HIV clinical research
- Operational HIV research
- Systematic reviews and meta-analyses addressing eligible research questions
- Generation of preliminary evidence for larger HIV research
Requirements
- The applicant must be the Principal Investigator of the proposed research project.
- The applicant must have obtained an MD, PhD, MBBS or equivalent terminal research degree after 30 September 2016.
- Master’s degrees and MPH qualifications alone are not considered qualifying terminal research degrees.
- The investigator must be serving for the first time as Principal Investigator on a substantial non-training research grant.
- Applicants who previously served as PI on a non-training grant exceeding US$30,000 are not eligible.
- The applicant must hold a qualifying research, academic, clinical or organisational position by the 30 September 2026 deadline.
- The applicant must hold citizenship of a low- or middle-income country.
- The applicant must identify a mentor with relevant expertise in paediatric and/or adolescent HIV research.
- A mentor commitment letter is required at the Letter of Intent stage.
- A letter of support from the applicant’s institution is required.
- The proposed research must address the current CIPHER thematic priorities.
- At least 80% of direct grant expenditure must occur in low- and middle-income countries.
- The host institution must have adequate research infrastructure to support implementation.
- Institutional indirect costs may not exceed 10%.
Application steps
- Review the official CIPHER Research Grant Programme 2026/2027 Call for Letters of Intent and FAQs.
- Confirm that the Principal Investigator meets the early-stage investigator and LMIC citizenship requirements.
- Select a research question aligned with the current paediatric and adolescent HIV thematic priorities.
- Identify an eligible mentor with relevant HIV research expertise.
- Prepare the Letter of Intent outlining the research background, specific aims, preliminary data where available and methodology.
- Obtain the required institutional support letter.
- Obtain the mentor’s letter of commitment.
- Prepare a scanned copy of the applicant’s qualifying terminal research degree.
- Complete the official online Letter of Intent submission form.
- Submit the Letter of Intent in English or French through the IAS online system by 30 September 2026 at 18:00 CEST.
- Shortlisted applicants will be notified by the end of November 2026 and invited to submit a full proposal by 30 January 2027.
A high-value research opportunity for emerging investigators in Africa and other low- and middle-income regions working on paediatric or adolescent HIV. The grant is designed specifically to help early-stage researchers lead substantial projects as Principal Investigators for the first time. Applicants should pay close attention to the terminal-degree date, prior-PI funding restriction, mandatory mentor and institutional support letters, and the requirement that at least 80% of direct grant expenditure be spent in LMICs. NGOs may participate where the Principal Investigator holds an established position in an organisation with adequate research infrastructure.